CIBA Vision Ophthalmics - Digital Grand Rounds


Digital Grand Rounds Program - Answer/Discussion

This is a case of nerve head drusen, or hyaline bodies. These formations are located anterior to the lamina cribrosa, and are present at birth, but can enlarge during puberty... sometimes dramatically. As seen, these bodies can obscure the disc margins, leading one towards a misdiagnosis of optic nerve head edema.

Hyaline bodies are suspected anytime you get this type of margin blurring without vascular changes. Do note that the disc itself is actually pretty clear... with little true 'blur' leading to poor visualization of the nerve head. No sign of inflammation is present either.

Rare cases can actually have some hemorrhage at the disc margin itself, with the surrounding vasculature still looking normal. A tough sell to say the least. Any of you who have the old Introduction to Ophthalmoscopy book from Upjohn that was given away to students 10-15 years ago can find a great photo of such hemorrhage.

Field defects of varying presentation can be sometimes found. Another interesting thing to note is the fact that these patients often have family members with the same condition.

See you next time!

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